Origin, dissemination and entry of the pandemic Zika viruses
Huimin Zhang - Personal Name
Youjun Feng - Personal Name
Swaminath Srinivas - Personal Name
Defeng Li - Personal Name
Zika virus (ZIKV) is a previously-neglected, but newly-emerging zoonotic pathogen that has swept most of the western hemisphere. The unexpected attention aroused worldwide lies in the explosive spread of ZIKV to Brazil and USA in 2015 and its rare correlation to micro-cephaly in newborns, raising a serious challenge to public health. We show the origin and fast dissemination of these epidemic ZIKA isolates. Phylogenetic analyses revealed that all the newly-emerging ZIKV isolates belong to the Asian-American Lineage. Structural analyses of the ZIKV E surface protein suggested that it might adopt a similar entry mechanism to that of other Flavi-viruses like Dengue Virus and West Nile Virus.
Availability
| EB00000002085K | Available |
Detail Information
Series Title
-
Call Number
-
Publisher
: ,
Collation
-
Language
ISBN/ISSN
-
Classification
NONE
Detail Information
Content Type
-
Media Type
-
Carrier Type
-
Edition
-
Subject(s)
Specific Detail Info
-
Statement of Responsibility
-
No other version available
File Attachment
