Regarding our article, we hypothesized the reasons why
Foschi D et al. showed a significant superiority of botulinum
toxin-A (BTA) versus placebo while the other three RCT did
not [2–5]. Surely, there are many other differences between
those trials and all of them may have led to the aforementioned
superiority. Foschi D et al. were the only ones who oriented
strict diet. Foschi D et al. have included only patients with BMI
greater than 35 kg/m2 while the others enrolled also Bless
obese^ individuals (BMI > 30 kg/m2). Foschi D et al. employe

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• Response to BThe Forgotten Fundus—Obesity Treatment with Botulinum Toxin-A Is Not Effective: a Systematic Review and Meta-Analysis^