Thymectomy is routinely carried out in patients
with myasthenia gravis (MG) and thymomas. However, there
is still a dispute as to whether MG patients with thymic hy-
perplasia should undergo thymectomy. We aimed to investi-
gate the pathological findings in the thymus in patients with
co-existing MG and thymic hyperplasia or thymomas treated
with thymectomy, as well as effects of immunosuppression.
Thirty-three patients with MG were selected and grouped ac-
cordingly: patients with no thymic abnormalities, patients
with thymic hyperplasia, and patients with thymomas. All
patients were treated with methylprednisolone alongside im-
munosuppression. A separate cohort of 24 MG patients with
thymic hyperplasia or thymomas and treated with thymecto-
my were selected. As controls, 5 patients with thymomas or

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• Pathological Findings in Myasthenia Gravis Patients with Thymic Hyperplasia and Thymoma