Photophobia is a common symptom seen in many neurologic disorders, however, its pathophysiology remains
unclear. Even the term is ambiguous. In this paper, we review the epidemiology and clinical manifestations of
photophobia in neurological disorders, including primary headache, blepharospasm, progressive supranuclear palsy,
and traumatic brain injury, discuss the definition, etiology and pathogenesis, and summarize practical methods of
diagnosis and treatment.

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• Photophobia in neurologic disorders