Background Mesenteric defect closure in laparo scopic gastric
bypass surgery has been reported to reduce the risk for small
bowel obstruction. Little is known, however, about the effect
of mesenteric defect closure on patient-reported outcome. The
aim of the present study was to see if mesenteric defect closure
affects health-related quality-of-life (HRQoL) after laparoscopic
gastric bypass
Methods Patients operated at 12 centers for bariatric surgery
participated in this randomized two-arm parallel study During
the operation, patients were randomized to closure of the mesenteric
defects or non-closure This study was a post-hoc analysis
comparing HRQoL of the two groups before surgery at 1
and 2 years after the operation HRQoL was estimated using
the short form 36 (SF-36-RAND) and the obesity problems
(OP) scale.
Results Between May 1, 2010, and November 14, 2011, 2507
patients were included in the study and randomly assigned to
mesenteric defect closure (n = 1259) or non-closure
(n = 1248). In total, 1619 patients (64.6%) reported on their
HRQoL at the 2-year follow-up. Mesenteric defect closure
was associated with slightly higher rating of social functioning
(87 ± 22.1 vs. 85 ± 24.2, p = 0.047) and role emotional
(85 ± 31.5 vs. 82 ± 35.0, p = 0.027). No difference was seen
on the OP scale (open defects 22 ± 24.8 vs. closed defects
20 ± 23.8, p = 0.125).
Conclusion When comparing mesenteric defect closure with
non-closure, there is no clinically relevant difference in
HRQoL after laparoscopic gastric bypass surgery.

EB00000002202K

Available

• Health-Related Quality-of-Life after Laparoscopic Gastric Bypass Surgery with or Without Closure of the Mesenteric Defects: a Post-hoc Analysis of Data from a Randomized Clinical Trial